Leucine-rich repeat flightless-interacting protein 1 Polyclonal Antibody

Catalog Number:

42245

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q32MZ4

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Leucine-rich repeat flightless-interacting protein 1 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Leucine-rich repeat flightless-interacting protein 1 polyclonal antibody.

Applications:

IHC

Background:

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

References:

[1]Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor.Reed A.L., Yamazaki H., Kaufman J.D., Rubinstein Y., Murphy B.A., Johnson A.C.J. Biol. Chem. 273:21594-21602(1998) [2]TRIP: a novel double strande

appl_detail:

Immunohistochemistry: 1:20 - 1:200

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