Product Datasheet
Leucine-rich repeat flightless-interacting protein 1 Polyclonal Antibody
Catalog Number: 42245
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q32MZ4
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Leucine-rich repeat flightless-interacting protein 1 protein
- appl_detail:
Immunohistochemistry: 1:20 - 1:200
- other_names:
- LRR FLII-interacting protein 1, GC-binding factor 2, TAR RNA-interacting protein, GCF2, TRIP, LRRFIP1
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Leucine-rich repeat flightless-interacting protein 1 polyclonal antibody.
- Background:
- Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
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