PTPN12 Antibody

Catalog Number:

37849

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q05209
NCBI Gene ID: 5782
Gene Accssion: NP_001124480/Q05209

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human protein tyrosine phosphatase, non-receptor type 12

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTPN12 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:300

Datasheet PDF