Product Datasheet
PTPN12 Antibody
Catalog Number: 37849
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q05209
NCBI Gene ID: 5782
Gene Accssion: NP_001124480/Q05209
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human protein tyrosine phosphatase, non-receptor type 12
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:300
- other_names:
- PTPG1; PTP-PEST
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PTPN12 protein.
- Background:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.?
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