NAIP Antibody

Catalog Number:

37749

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13075
NCBI Gene ID: 4671
Gene Accssion: NP_004527

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human NLR family, apoptosis inhibitory protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NAIP protein.

Applications:

IHC

Background:

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF