Product Datasheet
NAIP Antibody
Catalog Number: 37749
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13075
NCBI Gene ID: 4671
Gene Accssion: NP_004527
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human NLR family, apoptosis inhibitory protein
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- BIRC1; NLRB1; psiNAIP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NAIP protein.
- Background:
- This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1.?
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