MYO7A Antibody

Catalog Number:

37747

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13402
NCBI Gene ID: 4647
Gene Accssion: NP_000251

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human myosin VIIA

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MYO7A protein.

Applications:

IHC

Background:

This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF