Product Datasheet
MYO7A Antibody
Catalog Number: 37747
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13402
NCBI Gene ID: 4647
Gene Accssion: NP_000251
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human myosin VIIA
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- DFNB2; MYU7A; NSRD2; USH1B; DFNA11; MYOVIIA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MYO7A protein.
- Background:
- This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.?
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