MRGPRX1 Antibody

Catalog Number:

37739

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96LB2
NCBI Gene ID: 259249
Gene Accssion: NP_671732

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human MAS-related GPR, member X1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MRGPRX1 protein.

Applications:

IHC

Background:

MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF