Product Datasheet
MRGPRX1 Antibody
Catalog Number: 37739
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96LB2
NCBI Gene ID: 259249
Gene Accssion: NP_671732
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human MAS-related GPR, member X1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- GPCR; MGRG2; MRGX1; SNSR4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MRGPRX1 protein.
- Background:
- MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.
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