MAP3K11 Antibody

Catalog Number:

37733

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q16584
NCBI Gene ID: 4296
Gene Accssion: NP_002410

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase kinase kinase 11

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAP3K11 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:100

Datasheet PDF