Product Datasheet  
MAP3K11 Antibody  
Catalog Number: 37733  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q16584
    NCBI Gene ID: 4296
    Gene Accssion: NP_002410
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase kinase kinase 11
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:100

  • other_names：  
  • MLK3; PTK1; SPRK; MLK-3; MEKK11
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total MAP3K11 protein.
  • Applications：  
  • WB IHC
  • Background：  

  • The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.?




 
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