MCC Antibody

Catalog Number:

37718

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P23508
NCBI Gene ID: 4163
Gene Accssion: NP_002378

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mutated in colorectal cancers

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MCC protein.

Applications:

IHC

Background:

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF