Product Datasheet  
MCC Antibody  
Catalog Number: 37718  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P23508
    NCBI Gene ID: 4163
    Gene Accssion: NP_002378
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from internal residues of human mutated in colorectal cancers
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:50-1:200
  • other_names:  
  • MCC1
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total MCC protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.?



 
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