ARHGEF12 Antibody

Catalog Number:

37694

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NZN5
NCBI Gene ID: 23365
Gene Accssion: NP_056128

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Rho guanine nucleotide exchange factor (GEF) 12

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ARHGEF12 protein.

Applications:

IHC

Background:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF