Product Datasheet  
ARHGEF12 Antibody  
Catalog Number: 37694  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9NZN5
    NCBI Gene ID: 23365
    Gene Accssion: NP_056128
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human Rho guanine nucleotide exchange factor (GEF) 12
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • LARG; PRO2792
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total ARHGEF12 protein.
  • Applications：  
  • IHC
  • Background：  
  • Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.



 
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