JAG1 Antibody

Catalog Number:

37668

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P78504
NCBI Gene ID: 182
Gene Accssion: NP_000205/P78504

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human jagged 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total JAG1 protein.

Applications:

IHC

Background:

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF