Product Datasheet  
JAG1 Antibody  
Catalog Number: 37668  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P78504
    NCBI Gene ID: 182
    Gene Accssion: NP_000205/P78504
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human jagged 1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • AGS; AHD; AWS; HJ1; CD339; JAGL1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total JAG1 protein.
  • Applications：  
  • IHC
  • Background：  
  • The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.



 
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