IL17RB Antibody

Catalog Number:

37649

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NRM6
NCBI Gene ID: 55540
Gene Accssion: NP_061195

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human interleukin 17 receptor B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IL17RB protein.

Applications:

IHC

Background:

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF