Product Datasheet
IL17RB Antibody
Catalog Number: 37649
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NRM6
NCBI Gene ID: 55540
Gene Accssion: NP_061195
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human interleukin 17 receptor B
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- CRL4; EVI27; IL17BR; IL17RH1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IL17RB protein.
- Background:
- The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
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