IGF2R Antibody

Catalog Number:

37644

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P11717
NCBI Gene ID: 3482
Gene Accssion: NP_000867

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human insulin-like growth factor 2 receptor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IGF2R protein.

Applications:

WB IHC

Background:

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Datasheet PDF