Product Datasheet  
IGF2R Antibody  
Catalog Number: 37644  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P11717
    NCBI Gene ID: 3482
    Gene Accssion: NP_000867
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human insulin-like growth factor 2 receptor
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • MPR1; MPRI; CD222; CIMPR; M6P-R
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total IGF2R protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.



 
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