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MT-CYB Antibody

Catalog Number:

37517
other_names: MTCYB; CYTB

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P00156
NCBI Gene ID: 4519
Gene Accssion: YP_003024038

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded cytochrome b

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MT-CYB protein.

Applications:

IHC

Background:

Cytochrome b is a component of the ubiquinol-cytochrome c reductase complex, which is a respiratory chain that generates an electrochemical potential, coupled to ATP synthesis. The principal components of the b-c1 complex are cytochrome b, cytochrome c1, and the rieske protein. Cytochrome b posesses two heme groups, which are not covalently attached to the protein. Mutations in cytochrome b are associated with Leber¡¯s hereditary optic neuropathy and with myopathy.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF

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