Product Datasheet
MT-CYB Antibody
Catalog Number: 37517
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P00156
NCBI Gene ID: 4519
Gene Accssion: YP_003024038
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded cytochrome b
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MT-CYB protein.
- Background:
- Cytochrome b is a component of the ubiquinol-cytochrome c reductase complex, which is a respiratory chain that generates an electrochemical potential, coupled to ATP synthesis. The principal components of the b-c1 complex are cytochrome b, cytochrome c1, and the rieske protein. Cytochrome b posesses two heme groups, which are not covalently attached to the protein. Mutations in cytochrome b are associated with Leber¡¯s hereditary optic neuropathy and with myopathy.
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