PLA2G6 Antibody

Catalog Number:

37457

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60733
NCBI Gene ID: 8398
Gene Accssion: NP_003551

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human phospholipase A2, group VI (cytosolic, calcium-independent)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PLA2G6 protein.

Applications:

IHC

Background:

The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF