Product Datasheet
PLA2G6 Antibody
Catalog Number: 37457
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60733
NCBI Gene ID: 8398
Gene Accssion: NP_003551
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human phospholipase A2, group VI (cytosolic, calcium-independent)
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- GVI; PLA2; INAD1; NBIA2; iPLA2; NBIA2A; NBIA2B; PARK14; PNPLA9; CaI-PLA2; IPLA2-VIA; iPLA2beta
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PLA2G6 protein.
- Background:
- The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.
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