CACNA1E Antibody

Catalog Number:

37453

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15878
NCBI Gene ID: 777
Gene Accssion: NP_001192222

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human calcium channel, voltage-dependent, R type, alpha 1E subunit

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CACNA1E protein.

Applications:

IHC

Background:

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF