Product Datasheet
CACNA1E Antibody
Catalog Number: 37453
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q15878
NCBI Gene ID: 777
Gene Accssion: NP_001192222
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human calcium channel, voltage-dependent, R type, alpha 1E subunit
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- BII; CACH6; Cav2.3; CACNL1A6
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CACNA1E protein.
- Background:
- Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene
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