ALOX15 Antibody

Catalog Number:	37409
other_names:	15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15LOX-1; ALOX15;
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#: P16050 NCBI Gene ID: 246 Gene Accssion: NP_001127349
Form of Antibody:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage/Stability:
Immunogen:	Synthetic peptide corresponding to residues near the C terminal of human arachidonate 15-lipoxygenase
Purification:	Antigen affinity purification.
Specificity/Sensitivity:	The antibody detects endogenous levels of total ALOX15 protein.
Applications:	WB IHC
Background:	Arachidonate 15-lipoxygenase?is an?enzyme?that in humans is encoded by the?ALOX15?gene. The ALOX15 gene maps to 17p13.3 in close proximity to the tumor-suppressor gene TP53. The ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid.
References:
appl_detail:	Western blotting: 1:1000-1:5000 Immunohistochemistry: 1:50-1:200
	Datasheet PDF

Product Search