Product Datasheet
ALOX15 Antibody
Catalog Number: 37409
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P16050
NCBI Gene ID: 246
Gene Accssion: NP_001127349
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human arachidonate 15-lipoxygenase
- other_names:
- 15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15LOX-1; ALOX15;
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ALOX15 protein.
- Background:
Arachidonate 15-lipoxygenase?is an?enzyme?that in humans is encoded by the?ALOX15?gene. The ALOX15 gene maps to 17p13.3 in close proximity to the tumor-suppressor gene TP53. The ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid.
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