ACTA2 Antibody

Catalog Number:

37408

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P62736
NCBI Gene ID: 59
Gene Accssion: NP_001135417

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human actin, alpha 2, smooth muscle, aorta

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACTA2 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100

Datasheet PDF