Product Datasheet  
ACTA2 Antibody  
Catalog Number: 37408  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P62736
    NCBI Gene ID: 59
    Gene Accssion: NP_001135417
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the N terminal of human actin, alpha 2, smooth muscle, aorta
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:25-1:100
  • other_names:  
  • AAT6; ACTSA; MYMY5
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total ACTA2 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.



 
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