ASPN Antibody

Catalog Number:

37400

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BXN1
NCBI Gene ID: 54829
Gene Accssion: NP_001180264

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human asporin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ASPN protein.

Applications:

WB

Background:

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF