Product Datasheet
ASPN Antibody
Catalog Number: 37400
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BXN1
NCBI Gene ID: 54829
Gene Accssion: NP_001180264
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human asporin
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- OS3; PLAP1; PLAP-1; SLRR1C
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ASPN protein.
- Background:
- This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.
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