BRD4 Antibody

Catalog Number:

37393

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60885
NCBI Gene ID: 23476
Gene Accssion: NP_490597

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human bromodomain containing 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BRD4 protein.

Applications:

WB

Background:

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF