Product Datasheet
BRD4 Antibody
Catalog Number: 37393
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60885
NCBI Gene ID: 23476
Gene Accssion: NP_490597
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human bromodomain containing 4
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- CAP; MCAP; HUNK1; HUNKI
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BRD4 protein.
- Background:
- The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
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