NEK10 Antibody

Catalog Number:

37381

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6ZWH5
NCBI Gene ID: 152110
Gene Accssion: NP_955379

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human NIMA-related kinase 10

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NEK10 protein.

Applications:

IHC

Background:

Nek10 (NIMA (never in mitosis gene a)-related kinase 10) is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF