Product Datasheet
NEK10 Antibody
Catalog Number: 37381
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6ZWH5
NCBI Gene ID: 152110
Gene Accssion: NP_955379
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human NIMA-related kinase 10
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- FLJ32685; NEK10; Never in mitosis A-related kinase 10;
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NEK10 protein.
- Background:
- Nek10 (NIMA (never in mitosis gene a)-related kinase 10) is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.
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