AMZ1 Antibody

Catalog Number:

37348

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q400G9?
NCBI Gene ID: 155185
Gene Accssion: NP_597720

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human archaelysin family metallopeptidase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AMZ1 protein.

Applications:

WB IHC

Background:

AMZ1?shares sequence similarity with archaeal metalloproteases called archaemetzincins, but it appears to act predominantly as a basic aminopeptidase. Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF