Product Datasheet
AMZ1 Antibody
Catalog Number: 37348
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q400G9?
NCBI Gene ID: 155185
Gene Accssion: NP_597720
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human archaelysin family metallopeptidase 1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- AMZ1; Archaemetzincin-1; KIAA1950;metalloproteinase-like protein
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AMZ1 protein.
- Background:
- AMZ1?shares sequence similarity with archaeal metalloproteases called archaemetzincins, but it appears to act predominantly as a basic aminopeptidase. Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.
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