TFAP2B Antibody

Catalog Number:

37333

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q92481
NCBI Gene ID: 7021
Gene Accssion: NP_003212

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TFAP2B protein.

Applications:

WB

Background:

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF