Product Datasheet  
TFAP2B Antibody  
Catalog Number: 37333  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q92481
    NCBI Gene ID: 7021
    Gene Accssion: NP_003212
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the N terminal of human transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:200-1:1000
  • other_names:  
  • AP-2B; AP2-B
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total TFAP2B protein.
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.



 
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