Product Datasheet
TFAP2B Antibody
Catalog Number: 37333
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q92481
NCBI Gene ID: 7021
Gene Accssion: NP_003212
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- AP-2B; AP2-B
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TFAP2B protein.
- Background:
- This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
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