CASP9 (active) Antibody

Catalog Number:

37307

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P55211
NCBI Gene ID: 842
Gene Accssion: NP_001220

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human caspase 9, apoptosis-related cysteine peptidase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CASP9 (active) protein.

Applications:

IHC

Background:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF