Product Datasheet  
CASP9 (active) Antibody  
Catalog Number: 37307  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P55211
    NCBI Gene ID: 842
    Gene Accssion: NP_001220
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human caspase 9, apoptosis-related cysteine peptidase
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:100-1:300
  • other_names：  
  • MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; CASPASE-9c
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total CASP9 (active) protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.



 
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