TGFBR1 Antibody

Catalog Number:

37272

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P36897
NCBI Gene ID: 7046
Gene Accssion: NP_001124388

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human transforming growth factor, beta receptor 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TGFBR1 protein.

Applications:

IHC

Background:

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF