Product Datasheet  
TGFBR1 Antibody  
Catalog Number: 37272  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P36897
    NCBI Gene ID: 7046
    Gene Accssion: NP_001124388
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human transforming growth factor, beta receptor 1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • AAT5; ALK5; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total TGFBR1 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.



 
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