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PIK3CD Antibody

Catalog Number:

37826
other_names: APDS; PI3K; IMD14; p110D; P110DELTA

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00329
NCBI Gene ID: 5293
Gene Accssion: NP_005017/O00329

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIK3CD protein.

Applications:

IHC

Background:

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

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