Product Datasheet
PIK3CD Antibody
Catalog Number: 37826
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00329
NCBI Gene ID: 5293
Gene Accssion: NP_005017/O00329
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- APDS; PI3K; IMD14; p110D; P110DELTA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PIK3CD protein.
- Background:
- Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
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