MAGEB18 Antibody

Catalog Number:

37708

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96M61
NCBI Gene ID: 286514
Gene Accssion: NP_775970

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human melanoma antigen family B, 18

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAGEB18 protein.

Applications:

IHC

Background:

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF