Product Datasheet
MAGEB18 Antibody
Catalog Number: 37708
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96M61
NCBI Gene ID: 286514
Gene Accssion: NP_775970
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human melanoma antigen family B, 18
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MAGBI; MAGE-B18 antigen; MAGEB18;
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAGEB18 protein.
- Background:
- The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
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