Product Datasheet  
MAGEB18 Antibody  
Catalog Number: 37708  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q96M61
    NCBI Gene ID: 286514
    Gene Accssion: NP_775970
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from internal residues of human melanoma antigen family B, 18
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:25-1:100
  • other_names:  
  • MAGBI; MAGE-B18 antigen; MAGEB18;
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total MAGEB18 protein.
  • Applications:  
  • IHC
  • Background:  
  • The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.



 
© Signalway Biotechnology All Rights Reserved.